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Viagra and Prozac Stack: Interaction and Side Effects

Prozac is an effective drug for treating depression and compulsive disorders, it is not without side effects. Its use has been closely associated with a decrease in erectile function as many users have complained about experiencing decreased interest in sex.

Viagra and Prozac Stack

Customers of the drug consider combining it with ED remedies like Viagra, but one question lingers: is it safe and effective? Well, this guide answers that question. It equally sheds light on the benefits, side effects, and interactions of the individual drugs and what to expect by taking them.

What Exactly Is Prozac?

Prozac (often referred to as a “happy pill”), is a brand name for the generic drug fluoxetine. It is used to treat serious obsessive-compulsive disorder, depressive disorders, and a certain type of eating disorder, known as bulimia [1]. It works by interacting with serotonin — a neurotransmitter that is responsible for mood regulations and memory in the brain. It balances the neurotransmitter levels if it gets too much or too small in patients with the conditions mentioned above.

Prozac was first introduced in the United States in the ’80s and has since been one of the most prescribed antidepressants in the country. The drug has recorded tremendous success because of its ease of administration and minimal lethality in overdose [2]. As a result, it is considered as a milestone in psychiatry treatment.

The medicine has helped in raising awareness about depression and the danger that this illness portends in order to reduce the stigmatization associated with it [3].

What Is Viagra?

Viagra is Pfizer’s brand-name for sildenafil — a medicine used for treating erectile dysfunction in men. Erectile dysfunction commonly abbreviated as ED is the inability to achieve or maintain penile erection sufficient for satisfactory sexual performance.

Viagra Blue Tablets

Viagra was accidentally manufactured by Albert Wood and Peter Dunn — Pfizer scientists who were looking to develop a drug for angina pectoris and high blood pressure [4][5]. It was later patented in 1996, and approved by the Food and Drug Administration (FDA) as the first orally administered medicine for ED treatment. Due to its high success rate and safety, it has since soared in popularity, with more than 27 million prescriptions written [6][7].

The medicine works by helping to relax muscles in walls of blood vessels, which ultimately increasing blood flow to the penis. The increased blood flow then gives rise to erection and sustains it for pleasurable sex.

Combination of These Pills

About 30% to 70% of people who take antidepressant drugs usually suffer sexual dysfunction [8]. Prozac induces sexual dysfunction as one of its side effects. Fortunately, its users no longer have cause for alarm as studies have shown that it can be combined together with certain ED drugs to counter that effect.

The trial carried out revealed that its combination with sildenafil citrate (Viagra) brings about a slight improvement in ejaculatory latency time and sexual intercourse satisfaction, as compared with patients that were administered only fluoxetine [9]. The sexual dysfunction effect of antidepressants like Prozac is so common that it is often used as a sales pitch by marketers of drugs like Viagra.

Prozac and Viagra Side Effects

Besides the fact that it causes men to suffer sexual dysfunction, Prozac has some other known side effects. The most common ones include [10]:

  • nausea;
  • loss of appetite;
  • diarrhea;
  • dizziness;
  • insomnia;
  • tiredness;
  • increased sweating;
  • indigestion;
  • flu symptoms;
  • weight gain/loss.

On the other hand, the common adverse reactions associated with Viagra include:

  • headache;
  • burning;
  • nausea;
  • upset stomach;
  • flushing.

It may pose risks of more serious negative after-effects such as sensation priapism, and a transient decrease in blood pressure [11][12].

Side Effects of Medication

In rare cases, it may also cause loss of vision but it’s mostly associated with pre-existing medical conditions like diabetes, hypertension, mild and heart conditions [13].

Withdrawal Time

Some physical and mental symptoms may be experienced after reducing or stopping the intake of Prozac. Many individuals who use this medicine discover that they cannot quit the drugs without putting up a fight. The problem, according to psychiatry experts, is often associated with an improper diagnosis of clinical depression. Although Prozac produces physical dependence, the withdrawal time can be shortened with proper diagnosis and usage.

The withdrawal time is basically about two weeks for Prozac, and typical symptoms experienced include serious dizziness, confusion, and insomnia.

The propensity for people to develop withdrawal symptoms varies from person to person, the treatment for which it is given, and the dosage prescribed. Also is the time it would take for the antidepressant to disintegrate to half its original mass or size. Fortunately, it takes a long time for Prozac to stay in the system, causing fewer withdrawal symptoms than other antidepressants [14]. It is advisable to only use this drug under the supervision of a doctor.

On the other hand, there is no scientific evidence that Viagra is physically addictive. This is due to the fact that it does not interact with the brain’s reward pathways that trigger addiction and cause withdrawal symptoms.

Interaction with Food and Alcohol

Interaction with Food

A delay in effects may be experienced if Viagra is taken shortly before or after eating. However, there is usually no significant loss of efficacy [15].

Prozac, on the other hand, interacts with thiamine-rich foods like chicken liver, cheese, meat, soybeans, milk, etc. And this portends great danger based on its influence on blood pressure. Taking Prozac with caffeinated drinks like coffee or cola could also increase the risk of serotonin syndromes like sweating, confusion, diarrhea, high fever, and abnormal muscle movement [16].

Interaction with Alcohol

It may not be helpful to mix Viagra with alcohol. Alcohol itself depresses the central nervous system, thus slowing certain brain functions and activities including blood flow. Viagra, on the other hand, helps to increase blood flow to the penis to help have or keep an erection, which is counterintuitive to the workings of alcohol.

Taking both substances concomitantly may worsen side effects, as some of the side effects of intoxication are also common with Viagra – headache, extreme dizziness, rapid drop in blood pressure, and visual abnormalities. Long-term effects also include a decrease in testosterone levels.

In like manner, alcohol can worsen the adverse effects of Prozac such as drowsiness, difficulty concentrating, and dizziness. Some users may equally experience impairment in thinking and judgment.

The question: “Can I take Viagra with very little alcohol?” pops up very frequently. Well, this may be possible, as some healthcare providers agree that it’s OK to do so. However, for persons struggling with alcohol abuse, total refrain from taking Viagra and Prozac is highly advised.

What Are the Best Places to Buy Viagra and Prozac Online?

Prozac and Viagra can be purchased from local pharmacies, but their prices are a little on the high side, and they require a prescription. As a result, most men have found solace in patronizing online pharmacies.

Pills Online

However, it is important to apply caution when shopping online, so as to avoid buying counterfeit pills or getting scammed. The following are a few online pharmacies you can trust.

ViaBestBuys.com

This is a reputable and trustworthy online pharmacy that offers generic Viagra and a wide range of other ED drugs at an affordable price. However, it does not sell Prozac. ViaBestBuys has over a million customers and thousands of positive reviews powered by Yotpo. This speaks volumes of its credibility.

The vendor offers fast shipping delivery worldwide via Express Mail Service (EMS), except to Canada and a few other countries with stringent import laws. It equally ships via Registered Airmail, a slower but cheaper shipping method that is favorable for bulk orders. Typically, EMS shipments to the US, Europe, Australia, New Zealand, and the UK take 7–12 business days to arrive, while those shipped via Airmail take 10–18 business days. On the other hand, deliveries to other parts of the world may take 14-30 days. ViaBestBuys wastes no time, it ships packages within 2 hours after payment confirmation, and issues tracking numbers within 24-72 hours.

With online shopping, there is always the risk of the package getting missed, damaged, or delayed indefinitely at customers, but this vendor bears the full risks. That is, it provides a refund or reships packages free of charge if they do not get delivered.

One other great benefit of sourcing meds from this e-pharmacy is that it offers mouth-watering discounts and deals. Some of them include 30 free trial samples of generic Viagra, Cialis, or Levitra for individuals who may like to test the products before buying, 10 extra soft pills for returning customers, and an additional 20 extra tabs for buyers who leave a review.

ViaBestBuys accepts payment via Zelle, PayPal, credit cards, and Bitcoins, and guess what? There’s a 35% discount if payment is made via Bitcoins.

CialisBit.com

For individuals looking to get premium quality meds at the lowest possible price, CialisBit might be the perfect pharmacy. Like ViaBestBuys, it equally sells a wide range of medicines for ED. Unfortunately, it does not sell Prozac.

This pharmacy delivers products using two main shipping methods: Airmail and EMS. While parcels shipped to the US, Europe, Australia, New Zealand, and the UK via Airmail may take 10–18 business days to arrive, those shipped via EMS take 7–12 days, typically.

CialisBit supplies customers across the world, except those in countries with very stringent customer laws. Some of them include:

  • the United Arab Emirates;
  • Canada;
  • Israel;
  • Mexico;
  • Pakistan;
  • Brazil;
  • Indonesia;
  • South Africa;
  • Ireland;
  • Saudi Arabia;
  • Taiwan.

Regardless, CialisBit may still deliver to persons in these countries by using a parcel forwarding service.

Cialisbit.com Main Page

Buyers can save a whole lot by shopping with this vendor. It offers discounts such as 10 Viagra or Cialis soft tabs to returning customers, free samples, and a special 35% discount to persons who make payments with Bitcoin. And importantly, it provides free shipping for orders worth $80 for Registered Airmail and above $150 via EMS, as well as refunds or reshipment if the parcel goes missing.

HighStreetPharma.com

HighStreetPharma is also another online store to look at, it sells brand name ED meds like Viagra, Cialis, Levitra, etc., as well as their generic versions. It doesn’t have Prozac but can offer other antidepressants. It sources all its products directly from reputable manufacturers with FDA approval, and World Health Organization Good Manufacturing Practice (WHO GMP) certification. Thus, the quality of its products is 100% guaranteed.

HighStreetPharma equally offers two shipping methods: Airmail and EMS, and it ships products worldwide, including Canada. Typically, parcels sent via the former shipping method take 14–21 days, while those sent via the latter take 7–14 days to arrive. Though both shipping options have a price tag, the vendor provides free delivery for all orders worth $150 via Airmail Shipping.

Though the pharmacy offers a customer-centered refund policy that carters for missing, or damaged packages, it doesn’t apply to countries with strict customs laws. It accepts payments via credit cards and crypto, and it issues a 25% discount to customers who pay with the latter.

PureRxPills.com

PureRxPills is yet another reputable and trustworthy online pharmacy, but it operates quite differently. Unlike the aforementioned e-vendors that sell directly to customers, it pushes all orders to the best available vendor which then ships them to the specified location.

It offers a wide variety of FDA-approved medications including those for skincare, erectile dysfunction (Viagra, Cialis, Levitra, etc.), cancer, diabetes, and mental health, but it doesn’t offer Prozac.

It is worth noting that the vendor does not specify the delivery time, and it may vary based on location, the number of pills purchased, and delivery option used. However, it refunds its customers or reship their package if it goes missing, gets damaged, or stuck at customs.

PureRxPills can be trusted for high-quality pills, excellent customer service, fast delivery, flexible and secure payment process, as well as the best prices.

Resume

Prozac is a widely known and accepted antidepressant, and its use is popular due to the high prevalence of depression and the associated disorders in the world. Men taking it may suffer from erectile dysfunction.

Fortunately, it can be combined with Viagra to curb that adverse reaction. Research has shown that the mix is safe and quite effective. However, it is important to consult doctors before combining both drugs as they may need to experiment with Prozac dosage adjustment to see if it mitigates the associated sexual side effects.

Note: If you are not sure about the use of this drug, please consult your doctor.

References:

  1. Prozac (Fluoxetine): Side Effects, Dosage, Withdrawal, and Uses. By Joseph Nordqvist. Medically reviewed by Alan Carter. Retrieved: June 16, 2020. Medicalnewstoday.com.
  2. 25 Years After Prozac. By Randy C. Hatton, BSPharm, PharmD, FCCP, BCPS. Retrieved: June 16, 2020. Pharmacytoday.org.
  3. Classics in Chemical Neuroscience: Fluoxetine (Prozac). By Cody Wenthur, Megan Bennet et al. ACS Chemical Neuroscience. 2014 Jan 15; 5(1): 14–23. Retrieved: June 16, 2020. Ncbi.nlm.nih.gov.
  4. FDA Approves Viagra. Retrieved: June 16, 2020. History.com.
  5. Viagra: How a Little Blue Pill Changed the World. Medically reviewed by Leigh Ann Anderson, PharmD. Retrieved: June 16, 2020. Drugs.com.
  6. Sildenafil. Retrieved: June 16, 2020. Wikipedia.org.
  7. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. By James G McMurray, Robert A Feldman, et al. Ther Clin Risk Manag. 2007 Dec; 3(6): 975–981. Retrieved: June 16, 2020. Ncbi.nlm.nih.gov.
  8. Viagra Eases Depression-related ED: Treatment Lessons Sexual Side Effects of Antidepressants. Retrieved: June 16, 2020. Webmd.com.
  9. Effect of Fluoxetine Alone and in Combination with Sildenafil in Patients with Premature Ejaculation. By Mohammad Hosseini and Hooman Yarmohammaddi. National Library of Medicine. 2007; 79(1): 28-32. Retrieved June 24, 2020. Retrieved: June 16, 2020.Pubmed.ncbi.nlm.nih.gov.
  10.  Prozac. Retrieved: June 14, 2020. Drugwatch.com.
  11. Usw of Sildenafil (Viagra) in Patients with Cardiovascular Disease. By Melvin Cheitlin, Adolph Hutter et al. Circulation. 1999; 99: 168-177. Retrieved: June 14, 2020.Ahajournals.org.
  12. What Is ED? Viagra (Sildenafil Citrate). Retrieved: June 14, 2020. Safety Info. Viagra.com.
  13. The Dangers of Mixing Alcohol with Viagra. Medically reviewed by Dr. Gerardo Sison. By Addiction Campuses. Retrieved: June 14, 2020. Addictioncampuses.com.
  14. Many People Taking Antidepressants Discover they cannot Quit. By Benedict Carey and Robert Gebeloff. Retrieved: June 16, 2020. Nytime.com.
  15. Do Food and Dose Timing Affect the Efficacy of Sildenafil? A Randomized Placebo-Controlled Study. By Norman Zinner. The Journal of Sexual Medicine. 2007 Jan; 4(1): 137-144. Retrieved: June 16, 2020. Pubmed.ncbi.nlm.nih.gov.
  16. Fluoxetine and its Interactions with Food, Herbs, Alcohol, and Caffeine. By Madhumathi Palaniappan, Medically Reviewed by The Medindia Medical Review Team. Retrieved: June 14, 2020. Medindia.net.