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Viagra vs Revatio – What Is the Difference?

Viagra and Revatio are both highly potent health remedies. Sildenafil as an active ingredient is used to treat erectile dysfunction (ED) in men and pulmonary arterial hypertension (PAH).

What’s your health condition? What should you know before taking any of the drugs? Can you mix certain medications? This is the case of Revatio vs Viagra. Although they have the same active ingredient, some precautions must be adhered to.

Viagra vs Revatio

This guide contains pointers on how to safely take sildenafil for ED and PAH as well as a summary of the best online vendors selling these medications. Let’s acquaint ourselves with what’s necessary for the use of Viagra and Revatio.

What Exactly Is Revatio?

Pfizer is the maker of sildenafil. It discovered that this active ingredient could be used as a potent remedy for PAH. After numerous clinical trials, it showed a higher success rate in treating chest-pain related conditions.

It was approved by the FDA in 2005 as Revatio, marketed as a potent treatment for pulmonary arterial hypertension. It effectively improves exercise capacity in men and women and delays the worsening of the disease.

PAH is a rare, progressive disease that affects the lungs. It is characterized by high blood pressure in the lungs and causes symptoms such as dizziness and shortness of breath. This condition generally affects young and otherwise healthy individuals and normally strikes women twice as frequently as men. Also, every year, between 10 and 15 people per million population are diagnosed with PAH conditions. With improved treatments and survival, the number of U.S. patients living with the disease has increased to between 10,000 and 20,000 [1][2].

Revatio is a phosphodiesterase-5 (PDE5) inhibitor. PDE5 is an enzyme in the human body that is present in the smooth muscle of the arterial wall within the lungs. When hypertension occurs in the lungs, the heart’s mechanisms must work harder to pump enough blood through the lungs for adequate circulation in the body. As a remedy for PAH, sildenafil in Revatio works on the PDE5 enzyme in the lungs. It acts to dilate (or widen) the walls of the arteries, increasing blood flow and reducing the strain on the heart. Decreasing high blood pressure in the lungs allows the patient’s heart and lungs to work better and consistently improves the individual’s ability to exercise.

Full Information About Viagra

Was this medication a discovery? Certainly! Pfizer researchers en route to testing the most potent PAH remedy – sildenafil (the brand name Viagra), in clinical trials discovered that it could also be used to treat ED.

Viagra for Sexual Health

Those enrolled were getting a quality erection during sexual stimulation compared to their usual erection. Pfizer realized that Viagra could be a breakthrough medication and headed on to patent it.

In 1998, the FDA approved Viagra’s efficacy and safety as a potent remedy for ED. It also became the first treatment to be approved before its approval for PAH. Since then, millions of men have been prescribed with Viagra, thus making it the first, famous, and popular ED remedy.

Difference Between These Pills

It can be easy to confuse the active ingredient found in Viagra and Revatio. Although these drugs are marketed to treat different health conditions, they both contain the same primary ingredient — sildenafil. Both meds are also produced by the same approved manufacturer, Pfizer.

Viagra and Revatio are part of a family of drugs called PDE5 inhibitors. They work by increasing an important body substance called cGMP in the blood. This causes blood vessels to dilate, which results in different effects depending on the dose of the drug and treatment.

How can you compare Viagra vs Revatio? Here is a comprehensive table depicted the main similarities and differences between these pills:

Viagra Revatio
Drug class PDE5 inhibitor PDE5 inhibitor
Brand/generic status Brand and the generic version available Brand and the generic version available
What form does the drug come in? Oral tablet Oral tablet, injection, oral suspension
What is the generic name? Sildenafil citrate Sildenafil citrate
What is the standard
dosage?
50 mg 1 hour before sexual activity as needed 20 mg three times daily
How long is the typical treatment? Short term Short term or long term as directed by a medical specialist
Treatment condition Erectile dysfunction Pulmonary arterial hypertension
Off-label use? Female sexual arousal disorder and other health conditions as prescribed by a doctor
  • High altitude pulmonary edema;
  • Raynaud’s phenomenon and other health conditions as prescribed by a doctor.
Who typically uses the drug? Adults 18 years and older Adults 18 years and older

Sildenafil (as generic Viagra) has also been shown to help treat women who experience female sexual arousal disorder (or FSAD). This disorder is common in up to 26 percent of American women [3].

Depending on your health condition, Revatio or Viagra may be prescribed after a doctor assess your health. Talk to your medical specialist to find out which remedy may work better for you. Since they both contain the same ingredient, you may be prescribed generic sildenafil in most cases.

Where to Buy Viagra and Revatio?

What if you are diagnosed with ED? Or PAH? A doctor can recommend you to buy these medications at a local pharmacy or to order them from an online drug vendor.

Which option is better for your economic needs and privacy? Most men don’t like visiting a pharmacy to buy Viagra for ED. It’s an embarrassing experience. However, the emergence of online drug vendors takes away the worries.

Online Purchase

The following e-pharmacies are among the top best ED and other medication vendors sourcing their meds from approved manufacturers and offering them at favorable prices, unlike the higher cost you’d expect from a local pharmacy if it stocks these pills.

ViaBestBuys.com

Do you need genuine and quality ED medications? It’s necessary to shop online for Viagra and other ED meds from an e-pharmacy with the best health remedies. Customers trust ViaBestBuys because it is legit and trustworthy. And highly recommends it as the ultimate e-pharmacy for ED drugs including “smart drugs” – modafinil and others. Also, it offers Revatio.

ViaBestBuys product prices are extremely low. It also offers excellent price-reducing experiences such as coupons and discounts. Don’t worry about fake or low-quality medications. There is much to experience from this vendor. Best of all, it sources its products from legit and approved manufacturers. That’s the trust and confidence every buyer would like to experience from an online drugstore.

It ships packages to most parts of the world except Canada and the few other countries like Taiwan, Brazil, South Africa, Israel, Mexico, Indonesia, etc. due to their strict customs laws. What’s more interesting from this vendor? Enjoy the ultra-fast shipping of Viagra! Its delivery period for the available shipping options is as follows:

  • Express Mail Service (EMS) that takes from 7 up to 12 business days for orders from the UK, the EU, the USA, Australia & New Zealand and 14-30 days for the rest of the world;
  • Registered Airmail (its standard shipping option) takes from 10-18 business days for orders from the USA, the UK, the EU, Australia & New Zealand, and 14-30 days for the rest of the world.

Buy your medications, enjoy free shipping! This beneficial deal is available for orders above $80 (for standard delivery option) and above $150 (for the EMS). Besides, it has guaranteed delivery, and in case of any failure, it offers its customers free reshipping or refunds depending on customer’s choice.

When heading to check out, you can save more with the availability of a 35% discount when paying using Bitcoin (BTC). Furthermore, customers have the option to pay with PayPal, Visa Card, American Express, or MasterCard. Shop confidently! Head on to this e-pharmacy and experience safe and super secure protection – it’s the best bet for safety, affordable prices, and quality medications. Note that the more tablets you order, the lower the cost.

As a popular e-pharmacy selling ED drugs and extras, it has an excellent rating on the Trustpilot reviews portal. Verified buyers have rated this vendor as the most trusted due to its quality of medicines, pricing of products, and excellent customer support [4].

CialisBit.com

Just like ViaBestBuys, CialisBit sources its meds only from approved manufacturers. No need to worry about the quality of its meds including Viagra generics. Most customers trust this vendor and a high TrustScore, according to Trustpilot.com, proves it [5]. Shop with confidence and experience amazing discounts, coupons, and offers.

Cialisbit.com Main Page

The CialisBit e-pharmacy makes it easy to buy ED products, Revatio, and modafinil – one of the world’s first safe “smart drugs”! It offers its meds at the manufacturing cost. Besides, you get a chance to order free trial samples of Viagra. That impressive!

Its website is highly secured with an SSL certificate. Customers don’t have to worry about the safety of their payment options that include credit cards, PayPal, and Bitcoin (BTC). Checking out using BTC additionally earns you a 35% discount. At best, BTC is super-safe, highly secure, ultra-fast, and no transactions declined!

This vendor fulfills what it promises. It ships customer orders in discreet packaging to all parts of the world except Canada, Israel, Mexico, and a few other countries listed on its website. In case of any failed delivery, it offers free reshipping or refunds depending on the customer’s choice.

Shipping methods this vendor provides are as follows:

  • Express Mail Service (EMS). Delivery time – from 7 up to 12 business days for orders from the EU, the USA, the UK, Australia & New Zealand and 14–30 days for the rest of the world;
  • Registered Airmail takes from 10–18 business days for orders from the USA, the UK, the EU, Australia & New Zealand, and 14–30 days for the rest of the world.

Interestingly, save more money! Free shipping is available for orders above $80 sent via Airmail and above $150 shipped with the EMS.

HighStreetPharma.com

HighStreetPharma is yet another great online pharmacy we recommend. It offers a wide range of genuine health medications, including Revatio, at favorable prices. Although this e-pharmacy is not as popular as CialisBit and ViaBestBuys, it has the best customer support, genuine reviews, and loyalty.

It offers two shipping options: the EMS (7–14 days) and Airmail (14–21 days). If using the latter option, packages are not trackable and can take a maximum of 30 days to be delivered. The seller typically ships all customer orders within 2 hours after the buyer’s payment has been confirmed. Additionally, it offers a money-back guarantee. If your order doesn’t arrive at you within the stipulated time frame or the parcel gets damaged, you’ll get a full refund or your package will be reshipped free of charge.

HighStreetPharma ships worldwide. However, it does not offer reshipments or refunds to some other countries listed on its platform due to the strict customs and import laws they possess. Still, customers from those locations can buy products from this vendor and get them delivered using the Skypax.com forwarding service.

PureRxPills.com

PureRxPills is another excellent e-pharmacy, but it doesn’t offer Revatio and stands out from the mentioned ones. As stated on its website, it isn’t exactly an online drugstore. Instead, it is referred to as a pharmaceutical intermediary. Its primary goal is to help customers looking to get quality generic medications by effectively facilitating transactions between them and the manufacturers of the meds.

Buy with PureRxPills

To get drugs from this vendor, it requires its buyers to fill in some medical information. It’s necessary – especially if you haven’t visited a doctor. This information will be forwarded to a licensed physician to review and make informed decisions. Once your order is reviewed and approved, it will then be dispatched to your shipping address. If your parcel is shipped but doesn’t arrive or is damaged, this pharmaceutical intermediary will either offer you a refund or reship the order, depending on your preference.

Revatio vs Viagra: Dosage

For the treatment of heart conditions such as PAH, the recommended dose of Revatio Oral is 5 mg or 20 mg to be taken three times a day. It is administered 4–6 hours apart. In the clinical trial, no greater efficacy is achieved with the use of higher doses. Treatment with doses higher than 20 mg 3 times a day is not recommended [6].
The standard recommended dose of sildenafil used in Viagra or generics for treating ED is 50 mg, but your medical specialist can prescribe anywhere from 25 mg to 100 mg depending on your ED severity, tolerability, and response to medication.

When anticipating sexual activity, it should be taken 30–60 minutes earlier. Its peak effects are felt in an hour and last for 4–5 hours depending on your metabolism. Taking Viagra with fatty meals may delay the onset of action.

What Side Effects Do These Tablets Have?

Viagra and Revatio cause similar negative effects due to sildenafil contained in both drugs. Although not all of these symptoms may occur. Check with your medical specialist if any of the following common negative effects occur while taking sildenafil:

  • bladder pain;
  • burning, itching, crawling, numbness, prickling, “pins and needles”, or tingling feelings;
  • burning in the stomach or chest;
  • dizziness;
  • cloudy or bloody urine;
  • indigestion;
  • pain on urination;
  • increased frequency of urination;
  • tenderness in the stomach area;
  • stomach upset.

This is not a complete list [7]. If treating ED, Viagra has been studied comprehensively in regards to side effects and what you should follow before initiating dosage including important safety information and indication [8].

Interaction with Other Medicines

Sildenafil is mainly processed by the liver. Therefore, both of these drugs interact with many of the same medicines. Since Viagra and Revatio are processed by CYP3A4 enzymes, they should not be used with other meds that affect how these enzymes work. CYP3A4 inhibitors can increase the level of sildenafil in the blood and cause adverse negative effects.

Medications

Other drug interactions include:

  • nitrates;
  • antihypertensives;
  • HIV protease inhibitors;
  • alpha-blockers;
  • medicines that treat high blood pressure;
  • other drugs containing sildenafil or any other PDE5 inhibitors.

Do not take these meds together as this can increase the risk of hypotension or dangerously low blood pressure. This is not a comprehensive list of all possible drug interactions. Consult a medical specialist with all the medications you may be taking as well as to assess your health. It’s not good to take sildenafil if you have certain health problems.

Resume

Revatio, as a PAH remedy, contains the same active ingredient as Viagra for ED. Both medications can help treat different conditions depending on the dose given. Revatio by Pfizer comes with sildenafil at a lower dose, while Viagra tablets contain this component in higher doses. Both drugs should not be taken at once.

References:

  1. Pulmonary Hypertension (PDF). Retrieved: April 22, 2020. Thoracic.org.
  2. Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Badesch DB, Raskob GE, Elliott CG, Krichman AM, Farber HW, Frost AE, Barst RJ, Benza RL, Liou TG, Turner M, Giles S, Feldkircher K, Miller DP, McGoon MD. Published: February 2010. Ncbi.nlm.nih.gov.
  3. Sildenafil citrate for female sexual arousal disorder: a future possibility? Schoen C, Bachmann G. Published: April 2009. Ncbi.nlm.nih.gov.
  4. Viabestbuys – Buy Cheap Generic Viagra Online. TrustScore – Excellent. Retrieved: April 22, 2020. Trustpilot.com.
  5. Cialisbit – Buy Generic Cialis Online. TrustScore – Excellent. Retrieved: April 22, 2020. Trustpilot.com.
  6. Revatio Dosage. Retrieved: April 22, 2020. Drugs.com.
  7. Revatio Side Effects. Retrieved: April 22, 2020. Drugs.com.
  8. Viagra | IMPORTANT SAFETY INFORMATION. Retrieved: April 22, 2020. Viagra.com.
  9. Viagra | Wondering about possible side effects? Retrieved: April 22, 2020. Viagra.com.