Sertraline and Viagra: Result That You Should Expect

Erectile dysfunction (ED) has several root causes. Some medicines can worsen this condition. Apart from meds, there exist some other factors such as age, lifestyle, and health conditions that contribute to impotence [7]. However, various impotence drugs have been approved to reverse the problem men face during intercourse.

Viagra is the most famous ED drug. Sertraline is a medicine used as a remedy for a wide range of psychological conditions, including depression and anxiety.

How does a combination of sertraline and Viagra affect the patient’s health? Below are the answers to your questions. It also covers the best online vendors to order the drug of your choice.

What Exactly Is Sertraline?

Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat various psychological conditions, including the following:

• clinical depression;
• social anxiety disorder;
• fibromyalgia;
• premenstrual syndrome;
• body dysmorphic disorder;
• obsessive-compulsive disorder;
• post-traumatic stress disorder;
• bulimia;
• trichotillomania;
• agoraphobia;
• seasonal affective disorder.

As an SSRI, sertraline affects chemicals in the brain that may be unbalanced in patients with depression and other mood disorders. It works by preventing the reuptake of serotonin by nerves, leading to an increase in serotonin concentrations within the nerve synapse.

As a highly potent med that may be used to treat moderate to severe depression (major depressive disorder) or reduce feelings of anxiety in people with panic disorder, obsessive-compulsive disorder (OCD), or social anxiety disorder, it is also useful in relieving intrusion and avoidance symptoms associated with post-traumatic stress disorder (PTSD) and can help handle mood swings associated with premenstrual dysphoric disorder (PMDD) among other health conditions [1].

However, while its generics are available, it is recommended to take this med with precaution after consulting with a doctor. There is a higher chance of possible interactions and negative effects if taken without the aid of a medical specialist.

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What Is Viagra?

Viagra is a brand-name male impotence drug manufactured by Pfizer. It contains the world-famous and popular active ingredient known as sildenafil citrate [2].

People with ED use this drug as it’s highly potent in rectifying their condition. It makes men who need to engage in sexual intercourse get and maintain a strong erection. However, before administering any ED medicine, it’s necessary to first consult with a medical specialist to assess your health and recommend the right med that’s safe for your health.

Sildenafil inhibits the body natural enzyme called PDE5 that is responsible for affecting the production of nitric oxide (NO) needed to release cGMP. The cGMP is a chemical substance responsible for smoothening and softening the arteries.

By softening these vessels in the penile area, cGMP makes them relax and open up letting blood flow and circulate in the penis. And when sexually aroused, the availability of adequate blood circulation causes strong, firm, and hard erections, which can be maintained for complete and satisfying intercourse.

Although there are several male impotence drugs either branded or generic, Viagra is still the most favorable ED medicine used by several people globally.

Usage of These Pills Together

Some meds can be taken together without any effect, while others if taken together, can cause adverse interaction, which might be life-threatening or enhance each other’s benefits.

How about mixing sertraline and Viagra? Here is what you should acquaint yourself with.

How Effective Is Sertraline and Viagra for PE?

In a 1998 study, 46 men aged 22-63 with PE were given oral sertraline tablets. They took a dose of 25 mg per day before increasing to 50 mg by the third week and 100 mg per day by the sixth week. Before starting this medication, these men had a mean ejaculatory interval of 1 minute, with a range of 0-5 minutes.

Taking 25 mg of this drug boosted ejaculatory time from one minute to 7.6 minutes, with a range of 0 to 20 minutes. Administering 50 mg increased the ejaculatory interval to 13.1 minutes, and taking 100 mg increased it to 16.4 minutes. That’s how effective this drug is in treating PE [5].

Another research carried out to compare the efficacy and safety of sildenafil (Viagra) plus sertraline vs patients taking sertraline alone in the treatment of PE shows that sertraline coadministered with sildenafil can produce significantly improved results as a remedy for PE than using sertraline alone in patients with PE. However, the combined treatment can be associated with a slight increase in drug-related negative effects [6].

How About ED?

Under the brand name Zoloft, sertraline treats various mental disorders. It works by increasing the amount of the neurotransmitter called serotonin that is available in the brain.

Though increasing serotonin levels help relieve patient’s symptoms of depression or anxiety, this can also cause problems with sexual function.

How? With various theories for how antidepressants cause impotence, some reasons for using this drug suggest it can do the following:

• decrease feeling in sexual organs;
• block the action of nitric oxide;
• reduce the action of dopamine and norepinephrine neurotransmitters, hence decreasing the level of sexual desire and arousal.

By blocking the action of nitric oxide needed to relax the muscles and blood vessels, which allows adequate blood to flow to sexual organs, it makes a man unable to get or maintain an erection. However, by coadministering these two drugs – Viagra and sertraline, the effects of PE and ED are extremely lowered and a man can achieve the desired penile erection.

With this in-depth review of the two drugs, coadministering has positive rewarding effects. However, a medical specialist should take charge of assessing your health before prescribing this mix. Interaction and side effects can occur as mentioned below.

Viagra and Sertraline Side Effects

Like most effective medicines to treat various health conditions, negative effects cannot be fully avoided. Viagra is contraindicated with warnings and precautions that you need to familiarize with before taking it. Be sure to check everything including illnesses you have and drugs you take [8]. Above all, it’s paramount to talk with a doctor.

Viagra can cause these common side effects:

• headache;
• stuffy or runny nose;
• upset stomach;
• nausea;
• muscle pain;
• flushing;
• abnormal vision/blurred vision;
• dizziness;
• back pain;
• rash.

Depending on the patient’s health, such symptoms can occur differently. However, healthy men usually experience few (that come and fade away with continual use) to no negative reactions.

If beginning to take sertraline, chances of side effects such as thoughts about suicide may arise. For safe medication and precaution, the patient should stay alert to changes in their mood or symptoms. Reporting any new or worsening signs to a medical specialist is necessary.

Inform a doctor right away if you experience symptoms of serotonin syndrome, such as the following:

• hallucinations;
• loss of coordination;
• fast heart rate;
• sweating;
• fever;
• diarrhea;
• nausea;
• shivering;
• vomiting;
• twitching;
• muscle stiffness;
• agitation.

The severity of sexual problems caused by sertraline varies from person to person. For some men, negative effects decrease as the body adjusts to the medication. For others, the symptoms can persist.

Withdrawal Time

Viagra is a potent drug that is taken on an on-demand basis – not a daily dose. Once administered, its effects – the onset of action – can begin to be felt in less than 30 minutes and can last for 4-5 hours. It takes several hours for it to be fully removed from the body. It has no known physiological withdrawal symptoms.

Sertraline half-life is approximately 26 hours (range 22-36 hours) [9]. Its mean peak plasma concentrations (Cmax) occur between 4.5-8.4 hours after taking it [10].

However, sertraline discontinuation can lead to withdrawal symptoms, particularly if stopping is abrupt. The risk of such reactions may be dependent on several factors including the duration and dose of medication and the rate of dose reduction.

This can cause mild to moderate negative effects such as aforementioned, which usually occur within the first few days of discontinuing therapy. Sertraline should be gradually tapered over a period of several weeks or months with the help of a medical specialist.

Interaction with Food and Alcohol

While sertraline is used to treat various disorders, interference with other drugs and diseases can occur. Drug-drug interaction can cause adverse health reactions [11].

Likewise, ED meds such as sildenafil can cause various interactions and medical conditions if taken without letting a medical specialist assess the patient’s health. Be sure to thoroughly let the doctor perform complete health analysis to ensure safe medication with these two meds [8].

Lifestyle factors can affect the ability to have an erection. Smoking, alcohol drinking, and drug use can contribute to the problem. Moreover, stress and obesity can also add to the ED. If you smoke, try to quit. Also, avoid taking alcohol. This contributes to side effects when taking Viagra.

Although food has no effects, eating fatty meals can slow sildenafil’s onset of action. Also, the regular taking of large amounts of grapefruits/grapefruit juice can raise the levels of sildenafil in the body and delay its onset of action.

It’s also necessary to let a doctor know other medicine or products you take – either herbal remedies, vitamins, herbs, or OTC/prescription meds.

Moreover, avoid or limit the use of alcohol while being treated with sertraline. Alcohol can boost the nervous system chances of sertraline negative effects such as drowsiness, dizziness, impairment in thinking & judgment, and difficulty concentrating.

What Are the Best Places to Buy These Medicines?

Boosting male potency is possible with Viagra. Being high in-demand, it has become the most counterfeited drug in the world [3]. Antidepressants are sought after too, and the risk of running into scams always exists.

Therefore, it’s necessary to acquaint yourself with the best-approved manufacturers and online vendors that sell quality Viagra and sertraline. This info is covered below.

ViaBestBuys.com

Among the top-recommended male impotence drug vendors, ViaBestBuys takes the lead in providing approved, quality, and genuine ED products at an extremely low price, that are sourced from approved manufacturers.

Among other price-reducing customer experiences, it offers a whopping 25% discount just for checking out with bitcoin. However, you can still pay with a credit card or PayPal – whichever you prefer.

Delivery of Viagra is global to all parts of the world except Canada, Mexico, and some other listed countries due to country-specific strict customs laws. Care about your privacy? Orders are delivered in discreet packaging for the total security of your medicine via two possible methods: standard shipping, which takes 10-18 business days at a charge of $39 or Express Mail Service (EMS) taking from 7 up to 10 business days and worth $49. The former is free for orders over $130, and the latter – for orders above $180.

CialisBit.com

CialisBit tops the list of users’ testimonials about their experience with the drugstore they order their meds from. Above all, this recommended e-pharmacy sells approved meds sourced only from reliable manufacturers. However, a customer does business with such vendors that offer Viagra and other products at a favorable price.

Other than low-cost meds, its delivery is global except to very few countries such as Canada, Brazil, Mexico, and a few more.

What more can you ask from an e-pharmacy? Free delivery is approved for orders over $130 sent via standard shipping and orders over $180 shipped via EMS.

As an e-pharmacy that cares about customer privacy and security, all orders are sent in discreet packaging and the shopping experience via credit card, PayPal or crypto is secured with an SSL certificate. With the goal for a customer to save more, it’s made possible with offers, coupons, and discounts such as 25% off when checking out with Bitcoin.

HighStreetPharma.com

It’s a legit and trusted online drugstore selling approved meds from a wide variety of categories such as weight loss, diabetes, ED, HIV, hair loss, and a lot more.

As the drugstore states, it sources its products, including Viagra, only from approved manufacturers.

With its ultra-fast delivery, HighStreetPharma ships Viagra and other customer packages globally. However, it states that it does not give a refund or reshipment to the following countries due to country-specific strict customs: Brazil, Japan, South Africa, the UAE, some EU countries and a few others. Nonetheless, for countries that this e-pharmacy can successfully deliver to, it offers two delivery options:

• EMS – which takes 7-14 days;
• Airmail – taking 14-21 days.

Customers are given free Airmail shipping for Viagra and other ED orders above $150. Payments can be done either with gift cards or cryptocurrency.

PureRxPills.com

PureRxPills is another legit online drug vendor doing its business by satisfying customers with approved and quality ED meds at affordable prices.

Why this vendor? As it provides various categories of medications, including Viagra and sertraline, to treat health conditions, it tops our list as a highly trusted online seller.

Unlike some online drugstores that require a valid prescription for their products, ordering Viagra from this vendor doesn’t require one. A client needs, however, fill in the special medical form given by the site. With its highly secured website, ordering Viagra, sertraline, or other meds from this pharmacy is 100% risk-free and its global delivery is ultra-fast.

Promisingly, most of the products purchased from this e-pharmacy are eligible for free global delivery using Registered Airmail. However, unlike the aforementioned drugstores, PureRxPills has no list of countries it doesn’t ship parcels to due to their strict customs laws.

Conclusion

This has been an in-depth exploration of drug mixing and the results you should expect. Taking sertraline and Viagra together is safe, although monitoring and assessment by a doctor are recommended. Drug dose can play a very important role in how it affects the patient’s health.

While these two meds can be mixed with a favorable outcome, it’s necessary to know if taking it for PE and ED or other health problems. If you have both conditions, these two remedies can play a very important role.

Nonetheless, monitoring of side effects is recommended. For healthy individuals, adverse reactions can be minimal, although they can increase depending on the individual’s health and adherence to prescription. Always consult with your doctor prior to starting any treatments.

References:

1. Sertraline. Retrieved: February 23, 2020. Drugs.com.
2. Viagra. Retrieved: February 23, 2020. Viagra.com.
3. Up To 77 Percent Of Viagra Bought Online May Be Fake, And Possibly Dangerous, Research Shows. By Melanie Haiken. Published: Sep 12, 2013. Forbes.com.
4. 2 to 7 minutes (Patrick et al., 2005). Books.google.com.
5. Treatment of premature ejaculation with sertraline hydrochloride. McMahon CG. Int J Impot Res. Published: Sep 10, 1998. Ncbi.nlm.nih.gov.
6. Comparison between sildenafil plus sertraline and sertraline alone in the treatment of premature ejaculation. Zhang XS, Wang YX, Huang XY, Leng J, Li Z, Han YF. Zhonghua Nan Ke Xue. Published: July 2005. Ncbi.nlm.nih.gov.
7. Erectile Dysfunction: Could Zoloft Be Responsible? Retrieved: February 23, 2020. Healthline.com.
8. Wondering about possible side effects? Retrieved: February 23, 2020. Viagra.com.
9. Sertraline 50mg tablets. Retrieved: February 23, 2020. Medicines.org.uk.
10. ZOLOFT® (sertraline hydrochloride). Tablets and Oral Concentrate (pdf). Retrieved: February 23, 2020. Accessdata.fda.gov.
11. Sertraline Drug Interactions. Retrieved: February 23, 2020. Drugs.com.