Vyvanse and Cialis Together: Useful Guide to Mixing Drugs

Vyvanse is a super-effective medication used to treat attention deficit hyperactivity disorder (ADHD), but it can cause some sexual side effects, such as erectile dysfunction (ED) in some men. Cialis is one of the most popular medications for ED, so naturally, many men consider taking it to improve their sexual function.

However, before mixing them, it is important to understand the benefits, potential risks, and interactions that can result from taking both drugs together. You will learn about everything you need to know about that in this guide.

What Exactly Is Vyvanse?

Vyvanse is a prescription medication approved by the Food and Drug Administration (FDA) to treat attention deficit hyperactivity disorder in both adults and children 6 years of age and older. It is a central nervous system (CNS) stimulant that contains lisdexamfetamine as its active ingredient [1].

It works by raising the amount of dopamine, norepinephrine, and other neurotransmitters in the brain that are involved in the regulation of attention, mood, and behavior. The drug often causes a feeling of intense happiness, increases alertness, and boosts productivity. Consequently, some people misuse it to increase the euphoric feeling or take it off-label to enhance cognitive function and ultimately increase productivity [2].

Vyvanse is available in capsule form. It is typically taken once per day, either early in the morning or in the evening. However, doctors often adjust the dose based on the patient’s weight, age, and response to treatment. The drug is a controlled substance and should be used exactly as directed by a doctor or healthcare provider.

It is advisable to consult a doctor before starting treatment with it.

Brief Information About Cialis

Cialis is one of the most popular medications used to treat erectile dysfunction in men, as well as symptoms of benign prostatic hyperplasia (BPH). It contains tadalafil as its active ingredient. Tadalafil is a substance that belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the smooth muscles that line the walls of the blood vessels leading to the penis, ultimately increasing blood flow [3].

Cialis is available in tablet form and usually comes in 4 strengths: 2.5 mg, 5 mg, 10 mg, and 20 mg. Unlike most other ED medications, it can be taken in two ways: on an as-needed basis or a daily basis. The recommended starting dose for as-needed use is 10 mg, but it may be increased up to 20 mg if it doesn’t work. On the other hand, the recommended starting dose for the daily-use dose style is 2.5 mg but may be increased up to 5 mg if it doesn’t work [4].

It is worth noting that Cialis is a prescription medication and should be used correctly if the best is to be gotten out of it. It is not an aphrodisiac and does not increase sexual desire. It does not prevent sexually transmitted diseases (STIs) or pregnancy and is also not a cure for ED or BPH. Cialis is not recommended for use in women or children. It should also be used with caution in individuals with certain medical conditions, such as liver or kidney disease, heart disease, or a history of stroke or heart attack. It should only be used under the supervision of a healthcare provider.

Is It Safe to Combine Cialis and Vyvanse Together?

Many men who use Vyvanse experience problems with their erectile function after taking it for a while. In one study, researchers found the drug to be associated with ED in 2.6% of men [5]. Cialis is often looked at as an effective option for countering the sexual side effects of Vyvanse and ultimately improving sexual performance.

But can you take both drugs together? Is it safe?

Well, based on results from the interaction checker on Drugs.com, no serious interactions were found to result from the combined use of the medications. Consequently, you can take both drugs together, but it is worth noting that it may not be completely safe to do so [6].

Vyvanse and Cialis can affect blood pressure and heart rate; thus, combining them inappropriately can increase the risk of cardiovascular side effects. Additionally, although low, there is a potential for interaction.

Consult your doctor or healthcare provider if you feel the need to combine both drugs. Your doctor may recommend better treatment options for your ED or safe and effective dosing with a low risk of side effects if combining the medications is the best way forward. Do not try to combine the tablets yourself unless you’re being supervised by a healthcare professional.

Vyvanse and Cialis: Side Effects

Vyvanse and Cialis individually have side effects associated with their use. The sides may be mild and often go away without treatment; or more serious and become life-threatening if left untreated.

The common side effects associated with Vyvanse include [7]:

• decreased appetite;
• stomach pain;
• weight loss;
• diarrhea;
• nausea;
• loss of appetite;
• vomiting;
• Irritability;
• dry mouth;
• insomnia;
• dizziness;
• anxiety.

The above side effects are typically mild and tend to go on their own as the body acclimatizes to the drug. The more serious adverse effects include circulation problems, heart problems, neurological problems, severe allergic reactions, and psychiatric problems.

Additionally, Vyvanse sometimes causes sudden energy crashes when its effects wear off. If this happens, users may experience symptoms such as irritability, mood swings, tiredness, irritability, anxiety, depression, and nervousness.

On the other hand, the common side effects associated with Cialis include:

• headache;
• nausea;
• dizziness;
• flushing;
• nasal congestion;
• back pain;
• upset stomach.

More serious side effects that can result from Cialis use include priapism, a decrease of or sudden loss of hearing, severe allergic reaction, fainting, chest pain, hypotension, etc. These adverse effects can be life-threatening if left untreated. It is advisable to seek urgent medical attention should they arise.

At this point, it is worth noting that combining Vyvanse and Cialis may increase the risk of experiencing any of their individual side effects or worsen them. Additionally, it may increase the risk of interaction-based adverse effects.

It is important to talk to a doctor about any side effects that are experienced while taking either medication.

Withdrawal Time

Vyvanse may cause physical or mental symptoms if you suddenly stop or cut back on its use. Some of the common withdrawal symptoms include [8]:

• cravings;
• depression;
• increased appetite;
• increased need for sleep;
• anxiety;
• difficulty feeling pleasure.

The duration of the symptoms and severity may vary based on how long you have been taking the drug and how high the dose is. To prevent withdrawal symptoms, consult your doctor whenever you decide to stop taking the drug. Your doctor will taper off the dosage slowly over a few days or weeks.

Generally, Cialis is not physically addictive, and it is extremely rare to become reliant on it. However, there still remains a chance that it could become mentally addictive as you begin to rely on its results to have a healthy sex life.

If you are planning to stop either of these drugs, it is generally recommended to do so gradually, by reducing the dose over a period of time. This can help to reduce the risk of withdrawal symptoms and ensure that the medication is safely eliminated from your body. It is always best to talk to your healthcare provider before stopping any medication to determine the best course of action.

Interaction with Food and Alcohol

No serious interactions were found to result from combining Vyvanse and Cialis on the Drugs.com interaction checker. However, they both interact with alcohol, some drugs, and certain foods, and it is important to be aware of potential drug interactions when taking either of them. Let’s look at the individual substances Cialis and Vyvanse interacts with.

Here are some of the drugs that may interact with Vyvanse [9]:

• Monoamine oxidase inhibitors (MAOIs) – These meds are used to treat depression and should not be used alongside Vyvanse because they can cause a dangerous increase in blood pressure;
• Antidepressants – Vyvanse may interact with and increase the risk of side effects of some antidepressants, such as tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs);
• Blood pressure medications – Vyvanse can increase blood pressure, so it may not be suitable for people taking medications to lower blood pressure;
• Anticonvulsants – Vyvanse may interact with anticonvulsant medications and increase the risk of side effects;
• Antipsychotics – Vyvanse may interact with some antipsychotics and increase the risk of side effects, such as tremors and anxiety.

Do not take alcohol shortly before or after taking Vyvanse, as it can interact in a way that may increase the risk of adverse effects. It may also cause you to black out.

Some of the drugs that may interact with Cialis include [10]:

• metoprolol;
• amlodipine;
• nitrates such as isosorbide dinitrate or nitroglycerin;
• blood thinners;
• lisinopril;
• Viagra, Levitra, and other ED medications.

Cialis may not interact with alcohol in a dangerous way if it is taken moderately. However, note that excessive consumption can affect the effectiveness of the drug. Additionally, it interacts negatively with grapefruit, grapefruit juice, and fatty foods. While grapefruit and its extract can worsen or increase the risk of adverse effects, fatty foods may slow down its onset of effects and duration of action.

Note that this is by no means a comprehensive list of the full range of drugs Vyvanse and Cialis may interact with. It is important to consult a healthcare professional before combining these medications to determine whether it is safe to do so.

Best Places to Buy These Drugs Online

Today, there are countless online pharmacies that you can buy medications from. However, it is worth noting that not all of them are reliable. If you are interested in buying high-quality medications from vendors that offer the best possible prices and provide ultra-fast delivery, then you need to buy from trustworthy stores.

The best places currently to buy Cialis online are:

ViaBestBuys.com

ViaBestBuys is a reputable online pharmacy that ships Cialis and other sexual enhancement medications to most locations worldwide, with the exception of countries with strict import regulations. It sources its products directly from reputable pharmaceutical companies; consequently, they are guaranteed to be high quality. The company offers two main shipping methods: Express Mail Service (EMS) and Registered Airmail (standard delivery). However, for UK domestic deliveries and US domestic deliveries, it uses Royal Mail and USPS Priority Mail Express, respectively.

EMS deliveries to the US, Australia, EU, the UK, and New Zealand take 7-12 business days to arrive, while standard shipping to these countries takes 10-18 business days. Shipping to other countries not listed takes 14-30 days, regardless of the shipping method. UK-to-UK and US-to-US domestic deliveries typically arrive within 3-4 business days, sometimes overnight. ViaBestBuys has two fulfillment centers, one in Singapore and the other in India; it provides one of the fastest delivery by shipping from the center closest to the buyer’s shipping address.

In addition to selling ED drugs, such as generic Viagra, ViaBestBuys also offers attractive discounts, including 10 extra-soft pills for returning customers, a 25% discount for payments made with Bitcoin, and 20 additional tablets for those who leave an honest review after placing an order. It also provides free trial samples and free Airmail shipping on orders worth $80.

The company offers a 100% money-back guarantee, meaning it will provide a full refund or reship a package at no extra cost if it fails to deliver an order on time. Its accepted payment methods include cryptocurrency, PayPal, American Express, and MasterCard.

CialisBit.com

CialisBit is an online pharmacy that offers affordable prices for Cialis and other ED medications. Its primary shipping methods are EMS and Registered Airmail. EMS orders from the EU, the US, Australia, the UK, and New Zealand, usually take 7-12 business days to arrive, while Airmail orders take 10-18 days. Orders shipped to other parts of the world via either EMS or Airmail take 14-30 days to arrive.

To provide relatively faster delivery to customers, CialisBit uses Royal Mail for UK domestic orders and USPS Priority Mail Express for US domestic orders. These shipping methods typically result in delivery within 3-4 business days or even overnight.

CialisBit ships to most locations worldwide, with the exception of Brazil, Israel, the United Arab Emirates, Mexico, and other countries with strict import regulations. In some cases, it uses a parcel forwarding service called Skypax to assist buyers in such countries in receiving their packages. This service has a reported success rate of 99%, according to those who have used it.

CialisBit sources its products directly from manufacturers that have the necessary regulatory approvals, ensuring the quality of their products. On top of that, it offers a 100% money-back guarantee. That’s a win-win situation for buyers as it provides either a free reshipment or complete refunds if they (the buyers) are unsatisfied with their orders.

To keep customers loyal, CialisBit offers several profitable offers, including free shipping, free trial samples, and 10 free Cialis or Viagra tablets for returning customers. It also provides a 25% discount for payments made with Bitcoin. In addition to Bitcoin, CialisBit also accepts American Express, PayPal, and MasterCard; however, these payment methods do not qualify for any discounts.

HighStreetPharma.com

HighStreetPharma is a well-respected and reliable vendor with a history of providing excellent customer service. In contrast to the other pharmacies mentioned above, it sells a wide variety of products and ships them globally, including China, the United Arab Emirates, Canada, Russia, and more.

HighStreetPharma fulfills orders via both regular and express shipping. Orders sent via regular shipping take 14-21 days to arrive, while those shipped via EMS take 7-14 days. Customers who order medications worth at least $150 are eligible for free express delivery, and returning customers receive a 10% discount.

It’s worth noting that while this vendor ships worldwide, it does not offer a money-back guarantee for countries with strict import regulations. This means that if a buyer’s package is seized by customs at the border, they will not receive a refund or a free reshipment.

HighStreetPharma accepts multiple payment methods, including e-Check, all major credit cards, American Express, PayPal, and Amazon/Walmart gift cards. In certain regions, it also accepts cryptocurrency payments.

It is worth noting that neither ViaBestBuys.com, CialisBit.com, nor HighStreetPharma.com has Vyvanse in stock. They only sell Cialis, Levitra, and other FDA-approved ED medications. You may find Vyvanse on online pharmacies such as PocketPills.com and Walgreens.com.

Resume

Vyvanse and Cialis can be taken together, but it is only advisable to mix the pills under the supervision of a healthcare provider. This is because, although the chances of a negative interaction occurring are low, there remains a possibility. If you are considering taking these medications together, it is important to speak with a healthcare professional to determine the safety and potential risks. It is also important to follow the recommended dosage and usage instructions for both medications.

References:

1. What are Common Vyvanse Side Effects? For Adult ADHD. Retrieved: December 22, 2022. Vyvanse.com.
2. The Effects of Vyvanse on the Body. By Ann Pietrangelo. Medically reviewed by Rebecca Barnhart, PharmD, BCPP. Retrieved: December 22, 2022. Healthline.com.
3. Cialis (tadalafil): Dosage, side effects, how long it lasts, and more. By Jennifer Mitri Williamson, Pharm.D. Medically reviewed by Dena Westphalen, Pharm.D. Retrieved: December 22, 2022. Medicalnewstoday.com.
4. Should you take a daily erectile dysfunction pill? By Matthew Solan. Retrieved: December 22, 2022. Health.harvard.edu.
5. Vyvanse Adverse Effects and Safety Profile for ADHD. Retrieved: December 22, 2022. Vyvansepro.com.
6. Drug Interaction Report: Cialis, Vyvanse. Retrieved: December 22, 2022. Drugs.com.
7. Vyvanse side effects and how to avoid them. By SingleCare Team. Medically reviewed by Kristi C. Torres, Pharm.D. Retrieved: December 22, 2022. Singlecare.com.
8. Vyvanse Withdrawal Symptoms & Treatment. Retrieved: December 22, 2022. Withdrawal.net.
9. Vyvanse and Its Side Effects: What You Should Know. Written by Sharon Orrange, MD, MPH | Reviewed by Christina Aungst, PharmD. Retrieved: December 22, 2022. Goodrx.com.
10. Cialis Interactions Checker. Retrieved: December 22, 2022. Drugs.com.